The auction will benefit Barcelona's Vall d'Hebron University Hospital's art and health program.
The most famous NFT, a digital mosaic by the artist Beeple, sold for $69.3 million at Christie's last month.
The Picasso, which depicts the artist's lover and muse Marie Thérèse, is from 1932.
Cryptocurrencies' volatility remains a barrier to broader adoption.
“I think this is going to be a billion-dollar piece,” the buyer said to Bloomberg.
The house is about a three-minute bike ride from the Ocean Road beach.
A digital artwork by Beeple shattered every previous record set for the medium.
It may be a symptom of a continued decline in urban real estate caused by Covid-19.
Objects: USA 2020 is about to open in the design gallery R & Company in New York’s TriBeCa.
Sotheby’s sale of a Botticelli was a 787% increase from the artist’s previous auction record.
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